BDBM286984 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one::US10294223, Cpd No. 6::US11078199, Cpd 6::US9567334, Example 6::US9815834, Compound 6
SMILES CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCCN3CCN(CC3)C(=O)C=C)c2n1
InChI Key InChIKey=PUIXMSRTTHLNKI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 286984
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Principia Biopharma
Curated by ChEMBL
Principia Biopharma
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human CSF1R preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Principia Biopharma
Curated by ChEMBL
Principia Biopharma
Curated by ChEMBL
Affinity DataIC50: >1.50E+3nMAssay Description:Inhibition of human CSF1R by cell based assayMore data for this Ligand-Target Pair